Immunopathology of american cutaneous leishmaniasis. Modulation of MHC class II gene products by Keratinocytes before and after glucantime therapy

Histopathology of human American cutaneous leishmaniasis before and after treatment.

Chemical therapy for the treatment of leishmaniasis is still inadequate, and a number of drugs and therapeutic programs are being tested. Besides treatment, the ultimate goal is an effective cure, and histopathological analyses of the lesion cicatrices constitute an important measure of treatment success, or otherwise, in this respect. In this paper, we describe histopathological patterns in ca...

Class II Transactivator Modulation of Gene Expression by the MHC

tc1 cells percentage in patients with cutaneous leishmaniasis before and after treatment with glucantime

background: various responses and different prognosis to specific treatment in different patients from one hand, and importance of ifn-γ producer cells on the other hand impressed us to study tc1. methods: the study was conducted in ghaem medical center and bu-ali research institute, mashhad university of medical sciences, iran from 2001 to 2002. lymphocytes of 36 patients were counted and cult...

Comparison between intralesional Glucantime plus steroid and Glucantime in the treatment of cutaneous leishmaniasis

Introduction: Cutaneous leishmaniasis is a parasitic disease caused by various Leishmaniasis species and can result in a disfiguring scar. Hence, effective treatment is mandatory for prevention of the disease sequellae. The goal of this study was assessment and comparison of intralesional Glucantime plus steroid with intralesional Glucantime in the treatment of cutaneous leishmaniasis. Method...

Comparison of intralesional Glucantime alone with intralesional Glucantime and levamizole in cutaneous leishmaniasis

Background and aim: Cutaneous leishmaniasis is a common disease in the world and is an endemic disease in Iran. Highly variable results of systemic treatment of cutaneous leishmaniasis with levamisole have been reported in literature so far. The purpose of this study was to evaluate the efficacy and tolerability of levamisole as an adjuvant therapy with intralesional Glucantime.<br...